Bioengineering (BIOE)

BIOE 201. Introduction to Bioengineering I.

(3-0) Cr. 3. Prereq: CHEM 167
An exploration of cell structure and function, cellular metabolism, types of life forms, energy transport and use, biomolecule structure and function, and enzyme structure, function, and kinetics, with strong mathematical emphasis.

BIOE 202. Introduction to Bioengineering II.

(3-0) Cr. 3. Prereq: BIOE 201
Feedback loops in biological systems, cell and microbial growth patterns, fermentation kinetics. Biotechnology in diseases, wastewater treatment, genetic engineering of bacteria, fungi, plants, and animals, and biosensor operation. Strong mathematical emphasis.

BIOE 325. Systems Biology for Engineering.

(Cross-listed with E E). (3-0) Cr. 3. Prereq: BIOE 210, MATH 267
Review of systems approaches for modeling. Introduction or review of methods for gene regulation in cells and how to model them. Auto regulation of gene networks. Feedforward modeling, timing considerations. Feedback mechanisms. Kinetic and rate-limiting steps.

BIOE 341. BioMEMs and Nanotechnology.

(3-0) Cr. 3. Prereq: BIOE 210
Overview of Micro-Electro-Mechanical-System (MEMS) technologies for bioengineering, fundamentals of microfluidic device design, fabrication, and characterization, survey of microfluidic functional building blocks for lab-on-a-chip applications including mixers, valves, channels, and chambers. Topics of nanotechnology in bioengineering, nanoscale building block technologies for bioengineering including self-assembling, surface chemical treatment, nano-imprinting, nano-particles, nano-tubes, nano-wires, and stimuli-responsive biomaterials.

BIOE 341L. BioMEMS and Nanotechnology Laboratory.

(0-3) Cr. 1. Prereq: BIOE 210, concurrent enrollment in BIOE 341
Introductory laboratory course accompanying BIOE 341. Design, fabrication, and characterization of BioMEMS lab-on-a-chip devices and nanoscale techniques for bioengineering. Student group projects. BioE341L not a necessary corequisite with BioE341.

BIOE 352. Molecular, Cellular and Tissue Biomechanics.

(3-0) Cr. 3. Prereq: BIOE 210, E M 324, MAT E 273
Introduction to the anatomy of the musculoskeletal system and connective tissue. Range of movement, joint dislocation, bone deformity and fracture. Application of continuum mechanics to both living and non-living systems. Laws of motion, free-body diagrams and simple force analysis of musculoskeletal system. Biomechanical response of soft and hard tissues with emphasis on microstructure and mechanical properties. Applications to bioengineering design.

BIOE 411. Bioprocessing and Bioproducts.

(Dual-listed with 511). (Cross-listed with A E, C E, BSE). (3-0) Cr. 3. F. Prereq: A E 216 or equivalent, MATH 160 or MATH 165, one of CHEM 167 or higher, BIOL 173 or BIOL 211 or higher or BRT 501, senior or graduate classification
Sustainability, cleaner production. Taxonomy, kinetics, metabolism, aerobic and anaerobic fermentation. Biofuels, bioenergy and coproducts. Mass/energy balances, process integration, pretreatment, separation. Membrane reactors, bioelectrolysis, microbial fuel cells, nanotechnology, genetic engineering, mutagenesis.

BIOE 428. Image Processing with Biomedical Applications.

(3-0) Cr. 3. Prereq: E E 324
Review of signal processing, linear algebra, probability. Image sampling and quantization. Image transforms, image enhancement, image denoising/restoration. Tomographic reconstruction, segmentation and registration, recognition and shape analysis and applications in Computer Aided disease Detection (CAD).

BIOE 450. Biosensing.

(3-0) Cr. 3. Prereq: BIOE 210
Overview of biosensors and bioanalytical challenges; designing for performance including various analytical problems, ion-selective membranes, characteristics of enzymes and basics of bioaffinity sensing; fundamentals of bioselective layers including depositing films and membranes, surfaces for immobilization and bioselective agents; survey of different biosensing technologies including electroanalytical, biomembrane, optical, and acoustic-wave based sensors.

BIOE 450L. Biosensing Laboratory.

(0-3) Cr. 1. Prereq: BIOE 210, concurrent enrollment in BIOE 450
Laboratory course accompanying BIOE 450. Design, fabrication, and characterization of various electrical, chemical, polymer, optical and acoustic sensors. Lab is not a necessary corequisite with BIOE 450.

BIOE 490. Independent Study.

Cr. 1-3. Repeatable, maximum of 3 credits. F.S.SS. Prereq: chair for the Bioengineering Minor
Investigation of biomedical engineering topics of special interest to student and supervising faculty member with a final written report. Offered on a satisfactory-fail basis only.

BIOE 511. Bioprocessing and Bioproducts.

(Dual-listed with 411). (Cross-listed with A E, C E, BSE). (3-0) Cr. 3. F. Prereq: A E 216 or equivalent, MATH 160 or MATH 165, one of CHEM 167 or higher, BIOL 173 or BIOL 211 or higher or BRT 501, senior or graduate classification
Sustainability, cleaner production. Taxonomy, kinetics, metabolism, aerobic and anaerobic fermentation. Biofuels, bioenergy and coproducts. Mass/energy balances, process integration, pretreatment, separation. Membrane reactors, bioelectrolysis, microbial fuel cells, nanotechnology, genetic engineering, mutagenesis. Term paper for graduate level only.