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COMS 5690: Structural Bioinformatics

(Cross-listed with BCB 5690/ BBMB 5690/ CPRE 5690/ GDCB 5690).
Credits: 3. Contact Hours: Lecture 3.

Molecular structures including genes and gene products: protein, DNA and RNA structure. Structure determination methods, structural refinement, structure representation, comparison of structures, visualization, and modeling. Molecular and cellular structure from imaging. Analysis and prediction of protein secondary, tertiary, and higher order structure, disorder, protein-protein and protein-nucleic acid interactions, protein localization and function, bridging between molecular and cellular structures. Molecular evolution. (Typically Offered: Fall)