CPRE 5700: Systems Biology
(Cross-listed with COMS 5700/ BCB 5700/ GDCB 5700/ STAT 5700).
Credits: 3. Contact Hours: Lecture 3.
Algorithmic and statistical approaches in computational functional genomics and systems biology. Analysis of high throughput biological data obtained using system-wide measurements. Topological analysis, module discovery, and comparative analysis of gene and protein networks. Modeling, analysis, and inference of transcriptional regulatory networks, protein-protein interaction networks, and metabolic networks. Dynamic systems and whole-cell models. Ontology-driven, network based, and probabilistic approaches to information integration. (Typically Offered: Spring)